Where
appropriate,pharmacokinetic parameters were derived from non-compartmental analyses using the pharmacokinetic software,Win-Nonlin Ver.1.5 values of AUC(inf) and t(1/2) were reported when AUC(last) was over 80% of the AUC(inf).
如果条件适当,借助药物代谢动力学软件Win-Nonlin Ver.1.5,并利用非隔室模型分析法,会得到药物代谢动力学参数.当最终的血药浓度(AUC)超过80%的参考值(AUC inf)时,会得到血药浓度(参考值)与时间(二分之一)的数值.