B
考查表语从句的引导词，how如何，怎样，why为什么，what在句中做成分，主语或宾语，表语从句中不缺少主语和宾语，排除D，句意为：问题是我们如何才能帮助他，所以选择B
The question is ______ we can help him out of the trouble A．
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