As early
as the first century BC,man had found they could zoom the image by using spherical transparent
objects to observe small objects.Gradually can magnify the object to spherical surface imaging laws have to meet.In 1590,the Netherlands and Italy glasses makers have made similar microscopes microscope.In 1611,Kepler (kebole):the proposed compound microscopes make way.1876 Abbe (ABI):analysis of images produce a diffraction effect in microscope imaging,try to design the ideal microscope.1901
with Cajal (kajiaer) a group of organizations led by scientists
developed a method of staining of microscope,microscopic Anatomy set a
foundation for future.In 1930,Lebedeff (lebedeff):design and match the first interference microscope.In
addition by Zernicke (zhuoni Ko) phase difference microscope invented
in 1932,two people developed to extend the conventional optical
microscope observation of the phase difference allows biologists to
observe details of staining on living cells.1952 Nomarski (Nomarski):the invention of interference phase difference optical system.Not only the invention patented and named after the inventor himself.In
1981 Allen and Inoue (Allen and Inoue):on the principle of optical
micro-image-enhancing contrast,development tends to perfection.1988 Confocal (conjugate focal) scanning microscopy used widely in the market