Question

--she was very tired,she went on working.A; as B;although C;

Answer 1

in spite of之后只能加名词或名词性短语,不能接句子.比如 In spite of the weather,……这样.

(这里区别于despite,despite后可以加名词性从句如“Despite the fact that the public is getting increasingly discontented,但普通句也是不行的~)

就语法上的死规则,记住就好……

至于although~那就没啥限制了