【区别】when,while和as的区别：when引导的从句的谓语动词可以是延续性的动词,又可以是瞬时动词.并且when有时表示“就在那时”.例如：
When she came in,I stopped eating.她进来时,我在吃饭.(瞬时动词)
When I lived in the countryside,I used to carry some water for him.当的住在农村时,我常常为他担水.（延续性的动词）
We were about to leave when he came in.我们就要离开,就在那时他进来了.
While引导的从句的谓语动作必须是延续性的,并强调主句和从句的动作同时发生（或者相对应）.并且while有时还可以表示对比.例如：
While my wife was reading the newspaper,I was watching TV.(was reading是延续性的动词,was reading和was watching同时发生)
I like playing football while you like playing basketball.我喜欢踢足球,而你喜欢打篮球.（对比）
As表示“一边……一边”,as引导的动作是延续性的动作,一般用于主句和从句动作同时发生；as也可以强调“一先一后.例如：
We always sing as we walk.我们总是边走边唱.（as表示“一边……一边”）
As we was going out,it began to snow.当我们出门时,开始下雪了.（as强调句中两个动作紧接着先后发生,而不强调开始下雪的特定时间）
所以本题选择While更合适：强调主句和从句的动作同时发生（或者相对应）.
他在那个工厂工作的时候,学了很多.