1.不可以换
how在这里是副词,在句子中不作具体成分,而what是do的宾语,即do后面需要接成分,而what就是do要做的内容.
2.goes on和go on意思上是完全一致的,区别就是在形式上,goes是go的第三人称单数形式,而life就是第三人称,因此动词用goes,即goes on；第二句中,go是在will后面,因为will后面的一切动词都用原形,因此动词用go.
No matter how hard life it is.
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