What you have done and what you are doing make your mother angry.
这句谓语跟两个句子有关,因为What you have done and what you are doing 是两个句子连接的,有两个主语you,中间用并列连词and.You have done what and you are doing what ,是不是有两个主语和两个谓语,所以要用复数
What you have done and are doing makes your mother angry.
从这句可以看出差别,只有一个主语you,You have done and are doing what
是不是只有一个主语和谓语.
表语也是同样的道理,只是句子位置变了一下,