e made of sth 由什么制作的,制作的原料可以看得出来,仅是物理变化.如The desk is made of wood.
be made with sth 指“制作中用了什么东西”.如:
This bottle of grape soda water is made with real grape juice.这瓶葡萄汽水含有真正葡萄汁.(即这瓶葡萄汽水不是纯由天然果汁制作成的)
be made with 还可用于抽象意义.
另外还有 be made from sth. 制作的原料已经看不出来,发生化学变化了,如Paper is made from wood.