对于这个题目来说A是一点都不用怀疑的（有时会把which放在选项中就更难,但仍然需要选择as）
首先从语法角度来说,后面的从句is缺主语,所以用关系代词,排除CD,而B 不用非限制性定语从句
as用于定语从句中,与which的区别：
as引导的非限制性定语从句可放在主句前,而which不可以
as引导非限制性定语从句时有“正如”的意思,而which没有（这里就是这个原因）,一般有as you know,as is often the case 等
There is no simple answer ,( ) is often the case in science.
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